Intestinal Support Formula Vegetarian

Intestinal Support Formula Vegetarian

Intestinal Support Formula Vegetarian

Intestinal Support Formula (vegetarian) reduces immune and inflammatory responses by binding to and neutralizing bad bacteria and other toxins in the gut. As inflammation subsides, the gut is more able to heal, repair and absorb more nutrients.

  • Intestinal Support Formula is a supplemental form of immunoglobulins which are found naturally in the mucosal lining of the human gut.
  • Immunoglobulins can lead to significant improvement in digestive and non-digestive symptoms.
  • Immunoglobulins have been shown to help patients who did not respond to treatments like diet, probiotics, antimicrobials and soothing agents.
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  • Binds to bad bacteria and other toxins in the gut.
  • Gluten, milk free
  • Vegetarian formula made with immunized, powdered whole chicken eggs.

Suggested Use

  • Ideal for patients who do not fully respond to traditional gut treatments like diet, probiotics, antimicrobials and soothing agents.
  • Can be used periodically to quell a gut reaction or immune flare.  

Product Facts

  • A blend of immunoglobulins
  • Available as capsules or powder
  • Vegetarian formula
  • Free of wheat, gluten, soy, fish/shellfish, milk, tree nuts, and peanuts
  • No artificial flavors or colors ISF should NOT be the first therapy you try. Diet, probiotics and treating gut infections should always be the first step in your gut healing program.

The missing piece to optimal gut health & immune health is finally here.

ISF (Intestinal Support Formula) can lead to a healthier intestinal lining, improved nutrient absorption and an overall healthier you.

Why Dr. Ruscio Recommends it

  • Most gut therapies work to balance the bacteria and fungus in your gut. These therapies include dietary changes, probiotics and antimicrobial treatments.
  • Immunoglobulin supplementation is novel because it supports  the immune system instead. This is often the missing piece for those who have not responded fully to other therapies. Immunoglobulins bind to and neutralize gut irritants.
  • Immunoglobulin supplements work well for stubborn gut issues and have shown a high rate of success. I have been using the bovine-derived (non-vegetarian) Intestinal Support Formula with patients in my clinic and we have seen major improvements. Most patients tolerate Intestinal Support Formula very well.
  • While this is an exciting new development in IBS treatment, it’s very important to always try diet, probiotics and treating dysbiosis first.

What the Research Shows

The strongest research into immunoglobulins has been performed with bovine-derived formulas rather than the vegetarian egg-derived formula. Studies using bovine-derived formulas show exciting results:

  • Significant symptom improvement in IBS patients [1, 2, 3, 4, 5, 6, 7]
  • In fact, immunoglobulins have been shown to help IBS patients who did not respond to treatments like diet, probiotics, antimicrobials and soothing agents [8]
  • In a study by Weinstock: [9]
    • Patients were diagnosed with either SIBO, IBS or both
    • Then offered a few different treatments
    • In those who did not respond to any treatment, they were given immunoglobulins
    • A 75% response rate was noted!

A few studies have used egg-derived immunoglobulins. These are small and preliminary, but also promising:

  • A pilot study of 13 arthritis patients found improvement in arthritis symptoms and no adverse side effects. [10]
  • A small pilot study by a company that produces egg-derived immunoglobulins (this not the most credible source, but worth including because the results are exciting) showed that immunoglobulins can [11]:
    • Reduce leaky gut. In fact, Zonulin levels (a marker of gut permeability) decreased by 95%.
    • Decrease inflammation.
    • Increase beneficial flora.
    • Lower histamine levels.
  • One study successfully used a combination of probiotics and immunoglobulins to suppress H. pylori infections. [12]
  • Other studies show that, used orally, immunoglobulins help fight pathogens that cause periodontal disease (P. gingivalis) and tooth cavities (S. muttans) [13, 14]
  • This study shows a modest improvement in diarrhea in children infected with rotavirus. [15]
  • A handful of small, unpublished studies have also found promising results:
    • Improved mood, energy and digestive health in AIDS patients.
    • Significantly reduced inflammation, including a 42% reduction in CRP levels (an inflammatory marker).
    • Positive effects on pain, mood, depression and anger in active men after supplementing for just 10 days.

How to Use it


Take as capsules or powder, 1-2 times per day, with or without food.

5 grams per day is OK for most. Severe cases should consider 10 grams per day


As a long-term therapy for stubborn IBS and SIBO cases

Immunoglobulins have been shown to be especially effective for patients who have not been successful with other gut treatments.


As a short term treatment to quell an inflammatory flare

Immunoglobulins bind to and deactivate toxins in the gut. This helps to dampen the immune and inflammatory response.

What's Inside?

135 g
  • 135 g

Customer Reviews

Frequently Asked Questions

Why is it important to address diet, probiotics and other gut therapies before taking ISF?

Good gut health is critical to your overall health and it doesn’t pay to take short cuts. I encourage all patients to take the time to figure out the diet that works best, balance your microbiome and, if needed, treat gut infections. These steps will give you lasting results that no pill can duplicate.

How Soon Can I Expect Results?

You should notice an initial response by 1-2 weeks. Peak improvement is usually achieved by 6 weeks.  

Do Immunoglobulins Cause Negative Reactions?

Reactions may occur in a small number of patients, however, this supplement is generally well-tolerated.

Will Intestinal Support Formula Work for Me?

While every patient is unique, immunoglobulin supplements have shown very high response rates in clinical research. I have also seen positive responses to Intestinal Support Formula (bovine formula) for at least 50% of patients in my clinical practice.

The vegetarian formula is not as well-researched at regular Intestinal Support Formula, however it has similar properties and preliminary research is promising.