Probiotics have been studied in hundreds of randomized controlled trials, with demonstrated benefits across digestive, neurological, and immune health. These are the formulas we use every day in our clinic.
The largest body of probiotic research. Trials show benefits for bloating, gas, and regularity.
Your gut and brain are directly connected. Trials show benefits for mood, stress, and mental clarity.
A healthier gut also means a more balanced immune system, and often clearer skin.
Most probiotics give you just one formula. Triple Therapy combines all three of the most studied types in one daily stick, so you don’t miss out on any of the benefits. The dose, formulas, and duration come from a distillation of over 100 randomized controlled trials. We call these guidelines the Meta-Protocol.
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Did you know?
This is why quality control is crucial. Our probiotics are:
GMP-compliant: manufactured under Good Manufacturing Practices
3rd-party tested: independently verified, so what's on the label is in the bottle
Of every 10 probiotics on the market:
These are the formulas we use in my clinic. My approach is progressive but practical: I focus on strategies that work, avoid unnecessary expenses, and keep recommendations realistic.
Dr. Michael Ruscio, DC · Clinical Researcher · Adjunct Professor, University of Bridgeport
“I’ve been using the Triple Therapy Probiotic sticks for about 3 weeks and I have had a noticeable improvement in my digestive symptoms, so far!”
“I have found this product along with Soil-Based Probiotic and the Saccharomyces Boulardii Probiotic to be a winning blend. My gut has improved tremendously since taking these 3 products.”
The Meta-Protocol dosing guidelines
¼ tsp or 4 capsules (100+ billion CFU), 1 to 2 times a day
2 to 4 capsules, 1 to 2 times a day
1 to 2 capsules, 1 to 2 times a day, with food
Each probiotic has a dose range. Anywhere in the range is fine, more isn’t better.
Triple Therapy delivers all three formula types at their target dose, in one stick. An all-in-one source of the Meta-Protocol dosing guidelines.
Prefer to apply the formula types individually? We sell each one separately, one formula for each component of the Meta-Protocol.
average savings paying with pre-tax HSA/FSA dollars
Three categories of research-backed probiotics in one convenient package.
A blend of 12 probiotic species so you don't miss a single health benefit.
A well-researched yeast probiotic used to prevent, treat & heal GI issues.
Bacillus coagulans (the most studied soil-based probiotic) & B. subtilis species.
If you want the simplest path, go with Triple Therapy. It gives you all three formula types in one daily stick. If you'd rather start slow, the Lacto-Bifido Blend is the most well-researched category of probiotics and a great first step.
Yes. The three formula types work differently in the gut and complement each other. That is exactly why Triple Therapy combines them, and how we use probiotics in the clinic.
Some people notice changes in the first few weeks. We suggest a consistent 2 to 3 months before judging results.
Yes, qualified customers can. Choose Truemed at checkout and complete a short health survey (no doctor's visit). A licensed clinician reviews it, and if you qualify you receive a Letter of Medical Necessity. 90% are issued within 7 hours. Since HSA/FSA funds are pre-tax, most people save around 30%.
Every order is covered by our 100% money-back guarantee.
Bloating and gas are the most common reasons people start a probiotic, and the research base is strongest for multi-species Lactobacillus and Bifidobacterium blends. Start with the Lacto-Bifido Probiotic Blend, or cover all three categories with Triple Therapy. Give it a consistent 2 to 3 months.
Saccharomyces boulardii is a beneficial yeast, not a bacteria, so antibiotics don't kill it. That makes S. Boulardii the standard choice alongside a course of antibiotics and for rebuilding the gut afterward. It's also a common travel companion.
Some people feel worse on standard probiotics. Soil-based Bacillus species are spore-forming and tend to be gentler, which is why our Soil-Based Probiotic is where we point people who have reacted to other formulas. All of our formulas are hypoallergenic; full ingredient details are on each product page.
For stubborn gut issues, probiotics work best as one part of a broader plan. In our clinic that usually means pairing them with an elemental diet reset like Elemental Heal. The probiotics research guide on DrRuscio.com walks through the full approach.
Probiotics are among the most researched supplements in gut health, with over 100 randomized controlled trials covering digestion, the gut-brain axis, and immune function. Start with the formula that fits your situation, or take all three types at once with Triple Therapy. Many people pair probiotics with Elemental Heal for a full gut reset.
Try any formula risk-free. Every order is covered by our 100% money-back guarantee.
*Truemed is for qualified customers. HSA/FSA tax savings vary by individual tax bracket.
