Biota-Clear 1b

Biota-Clear 1b

Biota-Clear 1b

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Biota-Clear 1b

Biota-Clear 1b

The Biota Clear series provides powerful, botanical support for gut and immune function via multiple mechanisms:

  • Helps to restore healthy balance to the gut ecosystem*

  • Exerts powerful anti-bacterial, anti-fungal, anti-parasitic, and anti-biofilm activity*

  • Provides a milder alternative to prescription antibiotics and antifungals for stubborn gut dysbiosis*

  • Produces anti-inflammatory benefits and may have antidepressant effects*

  • May promote healthy motility* 

  • May reduce pain*

  • Long history of use by traditional cultures to treat digestive conditions*.

Wheat-Free

Wheat-Free

Gluten-Free

Gluten-Free

Soy-Free

Soy-Free

Casein-Free

Casein-Free

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Key Benefits

Gut Ecosystem Restoration

Helps reestablish a healthy gut balance with multi-faceted botanical support.

Anti-Microbial Action

Targets and neutralizes harmful bacteria, fungi, parasites, and biofilms.

Inflammation and Pain Relief

Offers potential anti-inflammatory and pain-reducing effects for greater comfort.

Promotes Digestive Health

Encourages healthy gut motility, aiding in the prevention of discomfort and bloating.

Why Choose
Biota-Clear 1b?

1
Potent Herbal Ingredients
Features a blend wormwood, black walnut, and other botanicals known for their gut-supportive properties.
2
Research-Driven Formula
Crafted based on published research and Dr. Ruscio's clinical insights for targeted, effective relief.
3
Purity and Safety
Prioritizes your health with a formula free from common allergens and artificial additives, ensuring a natural approach to gut health.

How to Use It

How to Use It

  • For correcting microbial imbalances in the gut:

    • Take 2 capsules twice daily together with Biota Clear 1a.

    • Rotate with Biota Clear 2a + 2b after one month.

    For ongoing health maintenance, take 2 capsules daily.

    Can be taken with or without food.

Breaking Through SIBO Biofilms

  • Biofilms may allow certain microbes to persist and limit treatment progress. In this video, I explain how our clinical team uses the Biota-Clear formulas in a rotating protocol designed to help disrupt biofilms and support healthier microbial balance.

  • Want to see how the full protocol works?

  • Explore the Biota-Clear Protocol →

What the Research Shows

  • Herbal preparations may be as effective as prescription antibiotics at treating SIBO and IBS [6].
  • Rotating antimicrobial treatments may be 20% more effective than a single treatment for remediating SIBO [10].
  • Berberine
  • A randomized clinical trial (gold standard research) found that 8 weeks of berberine reduced the frequency of diarrhea, abdominal pain, and urgency, and improved quality of life in IBS-D patients [5]. 
  • Animal study data indicates that berberine sets in train changes that may lead to reduced intestinal lining inflammation. Berberine also lowered gut sensitivity [11].
  • A systematic review / meta-analysis (SR/MA) of 13 randomized controlled trials (RCTs) found that adding berberine to standard therapy for H. pylori improved the eradication rate, raised the peptic ulcer healing rate, and reduced clinical symptoms and side effects (compared to standard therapy without berberine) [12].
  • A 2019 SR/MA of 5 RCTs found that berberine likely decreased serum CRP  (c-reactive protein) levels, thus relieving chronic inflammation [13].
  • Berberine reduced blood glucose, HbA1c, triglycerides, total cholesterol, and LDL-C compared with placebo [14].
  • A 2015 rat study found berberine improved IBS-D symptoms, possibly via opioid receptors [15].
  • Artemisinin (Artemisia annua, Sweet Wormwood) 
  • Artemisinin has been found in animal, in vitro, and some human clinical studies, to exhibit antimicrobial, anti-inflammatory, and gut microbiome modulating effects. For example:
  • Artemisinin helped in the treatment of malaria, resolving symptoms and  inhibiting malarial parasites (though with limited efficacy where parasites had developed resistance) [16, 17, 18, 19].
  • A 2020 study found that mice treated with dihydroartemisinin (DHA), a semisynthetic form of artemisinin, had, higher bacterial diversity (including increased Firmicutes and Saccharibacteria and decreased Deferribacteres and Actinobacteria relative to controls) [20].
  • In vitro studies show that artemisinin demonstrates anti-fungal and anti-yeast activity [21, 22].
  • Caprylic Acid 
  • Caprylic acid can reduce the bad bacteria animals and chickens carry in their guts according to a number of studies [23, 24, 25].
  • Neurodegenerative disease models suggest that caprylic acid may confer neuroprotective and mitochondria-protective effects and may strengthen antitumor actions in the case of brain cancer [26].
  • Black Walnut
  • An in vitro study found that black walnut tannins demonstrated antibacterial effects against Listeria, S. aureus, E. coli, Brochothrix thermosphacta, Pseudomonas fragi, Salmonella, and Lactobacillus plantarum [27].

Overall rating: 5.0 / 5 from 2 reviews.

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On the right track!

"I've been using the Biota-Clear regimen (1a through 2b) and all of the products have been bringing me long-sought relief. My system has also been calmer than it has in years. Really grateful to have found these products."

— Nicole N. (5/5)

Biota-Clear 1b fights SIBO

"I believe that Biota-Clear 1b has helped my body prevent SIBO. I take it as recommended and so far, so good."

— Randall B. (5/5)

Q&A

Frequently Asked Questions

Frequently Asked Questions

When Should I Start Taking Antimicrobials as Part of a Gut Healing Program?

Antimicrobials are Step 3 of my Great-in-8 gut healing protocol. Before taking herbal antimicrobials, it’s important to first set the foundation for gut health by getting adequate sleep, reducing stress, exercising, spending time in nature, improving diet and taking high-quality probiotic supplements. These foundational approaches set the stage for antimicrobial treatment and support long-term success once antimicrobial treatment is completed.

What’s the Suggested Duration of an Antimicrobial Treatment?

The Great-in-8 protocol recommends beginning with a 2-month course of treatment, rotating between Biota Clear 1a/1b and Biota Clear 2a/2b. An assessment at the end of the 2-month treatment will help you determine if additional treatments are needed.

Are Die-Off Reactions Possible?

Die-off reactions are an uncommon side effect that can occur when bad microbes die inside your body as a result of taking antimicrobials. Die-off may lead to:

  • Increased fatigue

  • Headaches

  • Digestive upset

  • Flu-like symptoms

Symptoms are usually temporary and are generally a sign that antimicrobial supplements are working. If symptoms last longer than a week, you may be intolerant of the herbal formula.

What Can I Do to Reduce Die-Off Reactions?

Reduce your dosage until you no longer experience reactions and then gradually increase to reach full dosage. If you continue to have symptoms, it’s best to switch to another herbal antimicrobial product.

Why Do You Sell Several Different Biota-Clear Products?

Research suggests that rotating antimicrobial treatments is 20% more effective than single treatments for remediating SIBO [10]. Rotating antimicrobials can also help to prevent antimicrobial resistance, which is when microorganisms adapt and become less susceptible antimicrobial agents. 

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